YMC-Triart C18 ExRS 層析管柱
YMC-Triart C18 ExRS採用有機雜化矽膠(hybrid silica-based)之高覆蓋率(high-coverage)C18液相層析管柱。 由於高碳載量(high carbon loading),YMC-Triart C18 ExRS的疏水性(hydrophobicity)很高,這使得YMC-Triart C18 ExRS適合與疏水性異構體(hydrophobic isomers)和結構類似物(structural analogs)使用。 有鑑於YMC-Triart C18 ExRS具有出色的化學和物理耐久性,可提供HPLC工作者在選擇分離條件時更大的靈活性,有利於進行分離方法開發和例行分析檢驗時使用。
SPECIFICATION | |
Base | organic/inorganic hybrid silica |
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Particle size | 1.9 μm, 3 μm, 5 μm |
Pore size | 80 Å |
Carbon contents | 25% |
Usable pH range | 1-12 |
USP | L1 |
POINT
■ C18 phase with high density bonding on inorganic/organic hybrid silica gel
■ Excellent selectivity for isomers and structural analogs
■ Superior chemical durability
■ Identical selectivity across different particle sizes
Features
A mixture that consists of compounds with various characteristics is analyzed with Triart C18 and Triart C18 ExRS. Triart C18 ExRS has lower polarity and higher hydrophobicity than the standard Triart C18 column, and also shows improved shape recognition.
1. Amitriptyline (basic compound)
2. 8-Quinolinol (coordination compound)
3. Testosterone (polar compound)
4. Naphthalene (π-π interaction)
5. Ibuprofen (acidic compound)
6. Propylbenzene (hydrophobicity)
7. n-Butylbenzene (hydrophobicity)
8. o-Terphenyl (planar cognitive ability)
9. Triphenylene (planar cognitive ability)
Column | : 5 µm, 150 X 3.0 mmI.D. |
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Eluent | : 20 mM KH2PO4-H3PO4 (pH 3.1) /methanol (25/75) |
Flow rate | : 0.425 mL/min |
Temperature | : 40°C |
Detection | : UV at 265 nm |
Injection | : 4 µL |
Triart ExRS is effective for separating structural analogs. This feature is especially useful for separating pharmaceuticals with structurally similar impurities.
Vitamin D2 and Vitamin D3
(Ergocalciferol)
(Cholecalciferol)
Column | : 5 µm, 150 X 3.0 mmI.D. |
---|---|
Eluent | : THF/acetonitrile (10/90) |
Flow rate | : 0.425 mL/min |
Temperature | : 30ºC |
Detection | : UV at 265 nm |
Injection | : 4.25 µL (10 µg/mL) |