YMC CHIRAL CD BR Series 手性分離管柱(不對稱/鏡相)
YMC CHRAL CD BR series is composed of 3 types of optical isomer separation columns. Each column possesses α-,β-,or γ-bromo-cyclodextrin as a functional group. Selection from the 3 types of columns enables analysis of a wide range of compounds. In addition, YMC CHIRAL CD BR series shows different selectivity from ODS because the separation is based on host-guest interaction. YMC CHIRAL CD BR series is useful for separating structural isomers that are difficult to separate using ODS.
SPECIFICATION
Particle size | : 5µm |
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Pore size | : 120Å |
Usable pH range | : 3.5-6.5 |
Column | ||
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YMC CHIRAL α-CD BR 250 x 4.6mmI.D. |
YMC CHIRAL β-CD BR 250 x 4.6mmI.D. |
YMC CHIRAL γ-CD BR 250 x 4.6mmI.D. |
Eluent | ||
0.1M CH3COOH-CH3COONa (pH4.0)/methanol(90/10) |
methanol/water (20/80) |
methanol/water (50/50) |
Flow rate | ||
1.0mL/min | 1.0mL/min | 1.0mL/min |
Temperature | ||
25ºC | 25ºC | 30ºC |
Detection | ||
UV at 254nm | UV at 254nm | UV at 230nm |
α-CD BR,β-CD BR,γ-CD BR show different separation feature because each of them has different size of cavities. Therefore choosing proper one can result in providing a successful separation of a wide-range compounds. It is also effective to use together with ODS columns.
Column | ||
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YMC CHIRAL β-CD BR 250 x 4.6mmI.D. |
YMC CHIRAL β-CD BR 250 x 4.6mmI.D. |
YMC CHIRAL γ-CD BR 250 x 4.6mmI.D. |
Eluent | ||
0.5M triethylamine- acetic acid (pH4.0)/ acetonitrile(10/90) |
0.5M triethylamine- acetic acid (pH5.4)/ acetonitrile(95/5) |
0.5M triethylamine- acetic acid (pH4.0)/ acetonitrile(60/40) |
Flow rate | ||
1.0mL/min | 1.0mL/min | 1.0mL/min |
Temperature | ||
25ºC | 25ºC | 25ºC |
Detection | ||
UV at 254nm | UV at 254nm | UV at 230nm |
YMC CHIRAL CD BR series provide better separation for various optical isomers because cyclodextrin is a chiral compound. YMC CHIRAL CD BR series is effective as a chiral column for reversed phase eluent.