YMC CHIRAL CD BR Series 手性分離管柱(不對稱/鏡相)

YMC CHRAL CD BR series is composed of 3 types of optical isomer separation columns. Each column possesses α-,β-,or γ-bromo-cyclodextrin as a functional group. Selection from the 3 types of columns enables analysis of a wide range of compounds. In addition, YMC CHIRAL CD BR series shows different selectivity from ODS because the separation is based on host-guest interaction. YMC CHIRAL CD BR series is useful for separating structural isomers that are difficult to separate using ODS.

SPECIFICATION

Particle size : 5µm
Pore size : 120Å
Usable pH range : 3.5-6.5
o-,m-,p-nitrophenol o-,m-,p-cresol α,β-estradiol
Column
YMC CHIRAL α-CD BR
250 x 4.6mmI.D.
YMC CHIRAL β-CD BR
250 x 4.6mmI.D.
YMC CHIRAL γ-CD BR
250 x 4.6mmI.D.
Eluent
0.1M CH3COOH-CH3COONa
(pH4.0)/methanol(90/10)
methanol/water
(20/80)
methanol/water
(50/50)
Flow rate
1.0mL/min 1.0mL/min 1.0mL/min
Temperature
25ºC 25ºC 30ºC
Detection
UV at 254nm UV at 254nm UV at 230nm

α-CD BR,β-CD BR,γ-CD BR show different separation feature because each of them has different size of cavities. Therefore choosing proper one can result in providing a successful separation of a wide-range compounds. It is also effective to use together with ODS columns.

Fenoprofen Chlorpheniramine Flurbiprofen
Column
YMC CHIRAL β-CD BR
250 x 4.6mmI.D.
YMC CHIRAL β-CD BR
250 x 4.6mmI.D.
YMC CHIRAL γ-CD BR
250 x 4.6mmI.D.
Eluent
0.5M triethylamine-
acetic acid
(pH4.0)/
acetonitrile(10/90)
0.5M triethylamine-
acetic acid
(pH5.4)/
acetonitrile(95/5)
0.5M triethylamine-
acetic acid
(pH4.0)/
acetonitrile(60/40)
Flow rate
1.0mL/min 1.0mL/min 1.0mL/min
Temperature
25ºC 25ºC 25ºC
Detection
UV at 254nm UV at 254nm UV at 230nm

YMC CHIRAL CD BR series provide better separation for various optical isomers because cyclodextrin is a chiral compound. YMC CHIRAL CD BR series is effective as a chiral column for reversed phase eluent.