YMC-Pack Pro C18 RS 層析管柱
Pro C18 RS由於具有高品質(high quality)的封端(end capping)，可用於分離鹼性化合物(basic compounds)得到出色的峰形(peak shape)。
Pro C18 RS由於具有高碳聚合物型(high carbon polymeric type)鍵結，因此具有高度立體選擇性(stereoselectivity)的辨識度。
Pro C18 RS可使用之pH範圍很廣（pH 1-10），有利於進行方法開發。
| SPECIFICATION | |
| Particle size | 3µm, 5µm |
|---|---|
| Pore size | 80 Å |
| Carbon contents | 22% |
| Usable pH range | 1.0-10.0 |
| USP | L1 |
POINT
￭ High selectivity,high carbon ODS column of polymeric type
￭ Excellent separation of basic compounds
￭ High quality end capping
￭ Attached 2 types of inspection sheet
￭ Low metal impurity silica base
￭ High reproducibility: batch to batch and column to column
￭ High durability
￭ Choice of a wide range of eluent conditions,easy development of method.
Features
pH 1
Pro C18 RS hardly change hydorophobicity of packing material in pH1 even 70ºC(column temperature)
Change of hydorophobicity of material in 70ºC after the replacement of the solvent in the column with acetonitrile/water/TFA(10/90/1),
pH 10
You can use RS in alkaline eluent in which you can not use general ODS column
Continuous analysis with 20mM H3BO3-NaOH(pH9.8)/methanol(50/50)
Separation behavior is influenced by changing the pH of the eluent. Pro C18 RS can operate over a wide pH range to allow manipulation of selectivity and retention.
1. Flurbiprofen 2. Methyl benzoate 3. Lidocaine 4. Diltiazem 5. Verapamil
Amitriptyline often exhibits peak tailing on competitive brands of columns but Pro C18 RS shows excellent peak shape for basic compounds.
1. Desipramine 2. Diphenyl (I.S.) 3. Imipramine 4. Amitriptyline
Pro C18 RS has excellent peak shape in a low-concentration TFA eluent that is suitable for LC/MS.
1. [Arg8]-Vasopressin 2. Bradykinin 3. Angiotensin II 4. Oxytocin 5. Angiotensin I 6. Leu-Enkephalin
