Nucleic acid therapeutics such as antisense, siRNA and aptamers are expected to play an important role as next-generation pharmaceuticals together with antibody drugs. These drugs demand chromatographic purification and analysis that can recognize slight structural differences following synthesis.
On this page, we provide useful tips for optimization of ion-exchange chromatography methods for oligonucleotides.
Read more “Optimization of oligonucleotide separations on ion-exchange chromatography”
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