Continuous Manufacturing & Analytics Webinar

Register today to attend Continuous Manufacturing & Analytics, our free-to-attend webinar series featuring novel technologies and advanced analytics that are enabling the implementation, optimization and scale up of intensified and fully-continuous processing.
Register: Continuous Manufacturing & Analytics Webinar

DAY 4 – JUNE 24, 2021
YMC Breakout Sessions:

First Session: Continuous Integrated Production of Therapeutic Proteins: The Role of Digitalization
The important role of digitization for advancing the implementation of continuous processing to the production of therapeutic proteins will be outlined by Prof Morbidelli
Speaker
Professor Massimo Morbidelli
Politecnico Milano

Second Session: Continuous Chromatography of Peptides: A CMO Perspective
The current modus operandi for the downstream processing of synthetic peptides is reversed phase chromatography performed in batch mode. Continuous chromatography is expected to be a disruptive technology for this very cost intensive part of synthetic peptide manufacturing. Results from a proof of principle study will be presented and compared to traditional batch chromatography
Speaker:
Dr. Ralf Eisenhuth
Process Manager Chromatography and Technology Transfer
Bachem

Third Session: How Certain Resins Further Accelerate MCC Gains
Speaker:
Dr. Hans Johansson
Global Application Director
Purolite Life Sciences.

Fourth Session: UV Based in Line Control of Twin-Column Continuous Countercurrent Chromatography; AutoPeak and AutomAb
The in-line control during the application of twin-column continuous countercurrent chromatography is crucial to optimize the yield during extended / continuous runs. Changing conditions such as degradation of Protein A resin (fouling) and / or titer of feedstock must be accounted for in the control scheme of multi-column chromatography. A patented in-line UV arrangement applied to either LPLC or HPLC versions of a twin-column system can automatically adjust operation “on-the-fly” without intimate operator intervention based on the user applied risk tolerance.
Speaker:
Thomas Müller-Späth, Ph.D
Chief Technical Officer
YMC ChromaCon AG